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However, optimal MMF therapy may be limited by gastrointestinal (GI) intolerance, which may result in the need for MMF dose reduction, interruption, or discontinuation, leading to increased risk of acute rejection.
There were no significant differences in survival and AIDS-free survival, occurrence of tuberculosis immune reconstitution inflammatory syndrome (IRIS), or treatment interruption or discontinuation by M. tuberculosis bacteremia status.
The interruption or discontinuation of ART might then have led to disease progression and death.
If these AEs are severe, dose reduction, interruption or discontinuation is recommended.
Neutropaenia was the primary reason for dose reduction, interruption, or discontinuation.
46– 49 Interruption or discontinuation of further scheduled cancer chemotherapy is an additional complication.
Similar(31)
Furthermore, our subgroup analysis showed that the total duration of lithium treatment was significantly longer in the hypercalcemia group, regardless of any possible interruptions or discontinuation of lithium treatment.
No treatment interruptions or discontinuation for cardiac toxicity and no treatment-related deaths were reported.
Neutropenia (17·8%), thrombocytopenia (9·2%), fatigue (8·3%), pneumonia (3·5%), pyrexia (3·5%), and anaemia (3·3%) were the most common adverse events that led to dose reductions, interruptions, or discontinuation.
The human cost of cancer-associated fatigue is high, as it may lead to interruption of or discontinuation of cancer treatment [ 16, 17].
The effectiveness, safety and cost-effectiveness of potential combinations during hospitalization, the duration of therapies, interruptions, or discontinuations as well as their reasons and possible consequences are unknown.
More suggestions(15)
discontinuation or discontinuation
interruption or multitasking
interruption or reduction
interruption or fuss
interruption or switching
interruption or clarification
interruption or step-off
interruption or modification
interruption or dose
interruption or duration
interruption or task
interruption or defense
interruption or regression
interruption or death
interruption or change
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