Your English writing platform
Discover LudwigExact(3)
The primary end points were all cause mortality and adverse events leading to an interruption of trial drug.
For confirmed serious adverse events which were trial exclusions, the protocol required either a permanent or a temporary interruption of trial treatment (see Additional file 1).
Suspected adverse events leading to a planned interruption of trial drug occurred in 18 patients (12 co-trimoxazole, 6 placebo); all except six (all co-trimoxazole) resumed the trial drug.
Similar(57)
Daily interruption of sedation trials (IS-trials) have been implemented in many surgical and medical ICUs after randomized controlled trials demonstrated that IS decreased the duration of mechanical ventilation, shortened the hospital stay and may, in combination with spontaneous breathing trials, improve outcome in medical intensive care patients [ 2- 6].
In brain-injured patients undergoing mechanical ventilation through a tracheotomy, we found the rate of reconnection to the ventilator much higher than expected, which led us to early interruption of the trial.
Indeed, the difficulties in recruiting patients in AdCare, mostly due to complexities in the informed consent procedure, determined the anticipated interruption of the trial.
Although the present results demonstrate the superiority of one of the methods, we have to recognize that the early interruption of the trial is a limiting factor.
In addition, the DMSC may recommend interruption of the trial at any time if safety concerns arise upon SAE evaluation or due to other reasons.
ScienceInsider this week reported on a U.S. government official's prediction that H1N1 flu will continue unabated during the summer and into the fall, a decision by the G8 nations to skip science at their summit meeting in Italy this month, and an interruption of clinical trials caused by procedural errors at two U.S. cancer centers.
Breaking fixation resulted in the interruption of the ongoing trial.
The toxicity was described as "intolerable" and caused interruption of the clinical trials.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com