A person who is on a drug such as Efavirenz can develop resistance after as little as a two-day interruption of treatment.
Individuals infected with HIV-1 require lifelong antiretroviral therapy, because interruption of treatment leads to rapid rebound viraemia.
Patients receiving HD IL-2 treatment often experience severe adverse side effects, which result in the interruption of treatment.
Under-treatment may then be suspected, with interruption of treatment before complete tumour remission due to feared renal toxicity.
For example, ponds operating in parallel prevent interruption of treatment during the cooler months of the year.
Except for three subjects, the gum adverse effects occurred early during treatment, did not cause interruption of treatment, and resolved rapidly and completely.
In a mean period of 8.6 months, 27% of responders to CBZ incurred in undesired effects to a level that caused interruption of treatment or a dosage reduction to an unsatisfactory level.
Nearly 40% of patients who defaulted and >28% of the non-defaulters had at least 1 interruption of treatment during IP.
Similar conclusions have been drawn by Trkola et al. in chronically infected patients subjected to short-term interruption of treatment [50].
On December 16, 2008, the Minister of Health issued a 'Nota' (a sub-legislative act) forbidding the interruption of treatment for disabled people hospitalized within the National Health Service.
For non-responder patients from the HCV T group a second serum sample taken after interruption of treatment (6 or 12 months after its start) was available and included in the study.
