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Our results support that daily interruption of sedation may decrease the need for head CT in sedated, mechanically ventilated patients.
If the patient was sedated, MDRS score and CAM-ICU were assessed ≥6 h after interruption of sedation.
Daily interruption of sedation was mandatory, except in hemodynamically unstable patients.
In clinical contexts where this is not possible or not desirable, daily interruption of sedation is encouraged.
In all patients treated with sedatives, daily interruption of sedation was an integral component of the sedation protocol.
We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of no sedation versus daily interruption of sedation.
We compared extubation time following daily interruption of sedation in intensive care unit patients with renal impairment with two sedation regimes remifentanil midazolam and fentanyl midazolam.
Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation.
Intermittent sedation and daily interruption of sedation were feasible strategies in order to reduce the burden of sedation overuse in a low nursing staff ICU.
Improvements in sedation practice (including daily interruption of sedation [DIS]) have been strongly associated with decreased ICU length of stay and decreased duration of mechanical ventilation [1].
To reduce the interference of sedation in mechanically ventilated patients, ICDSC assessments were performed in mechanically ventilated patients after routine daily interruption of sedation at our institution.
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