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In order to define the product of the TES reaction in more detail, we modified the sequence of the branch point to introduce an interrupted site for the restriction enzyme SacI across the junction.
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The WNA analogue consists of an aromatic ring and a recognition base on the bicyclic skeleton, and the recognition of the CG or TA interrupting sites has been achieved by the WNA analogues.
For the rate of creation, we must treat interrupting sites differently depending on whether there are transitions or transversions.
Define κ as the ratio between of the rates of transition and transversion and λ the fraction of interrupting sites that are transitions.
Here, among the interrupting sites of P 8 loci, we observe a fraction λ = 0.47 of transitions; assuming κ = 6 (based on table 1; since there are two possible transversions for each transition, κ = 2 × Ts Tv), this leads to an expected frequency for the S 8 allele of 0.061.
TFO containing the 3′-dA-1-dG context recognized the CG interrupting site, and that with the 3′-dG-1-dG context recognized the GC site.
Novel nucleoside analogs have been designed for selective formation of anti-parallel triplexes including a TA or a CG interrupting site.
Among the comparisons, 5 (3.9%) at the Shezi site and 7 (6.7%) at the Neverest site interrupted ART.
When stimulation at a site interrupted motor, sensory or language function, afterdischarges were more likely to occur at other sites where stimulation interrupted similar functions.
Mutant allele T interrupts binding-site of miR-1207-5p while creating new binding-sites for miR-940/4514/4692.
The cortical line of the spine was interrupted, representing the site of the avulsion.
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