The computer glitch apparently interrupted signals from a laptop computer inside the station that serves as a command panel for the departing ATV-3 spacecraft.
DHA treatment was associated with down-regulated pro-inflammatory cytokine production, reduced antimicrobial capacity, a weak oxidative response, diminished phagolysosome maturation, and interrupted signaling events critical for IFNγ-induced cell activation.
The suppression of a diverse range of transcripts further indicates interrupted signaling, but more work would need to be performed to confirm this.
Condensed chromatin fibres appeared as thick continuous lines; thin fibres, observed as beaded, interrupted signals, are the result of maximally decondensed DNA fibres.
Interrupting signal transduction in the VNO appears to have consequences beyond acute pheromone detection.
For instance, Wip1 interrupts signal transduction pathways by dephosphorylating ATM and other proteins [ 29] (e.g. interaction 21).
That is to say, although there have been upregulated apoptosis signals in the cytoplasm after irradiation, negative feedback of nucleic apoptosis signals might interrupt signal transmission downstream of caspase cascades to the nucleus and trigger the antiapoptosis effects.
This finding indicates that β-strand and helix mimetics may both serve as inhibitors of enzymatic function not by direct targeting of the catalytic pocket but by interrupting signal transduction pathways mediated by certain enzymes.
