We demonstrate a highly cost-effective system capable of simultaneously interrogating a sample under SPRM and SPRF, thus spatially discriminating between regions on the same sample.
Subsequent to securing permission from consultants responsible for the care of patients, the hospital information system was interrogated to identify a sample of eligible patients aged 18 and over, at least 6 months and no >5 years after a diagnosis of invasive cancer (between 1 April 2004 and 30 June 2009), who had been treated with curative intent.
We interrogated a range of samples including human cell lines, primary tumours and primary tissue samples.
We chose the four additional compounds shown in Figure 1 to interrogate a large sampling of rat octanal ORs for evidence of octane-1,1-diol recognition.
We interrogated a set of donor-matched atherosclerotic and normal aortic samples ranging from histological grade III to VII, with a high-density (>450,000 CpG sites) DNA methylation microarray.
We have in addition interrogated a number of whole-block tissue sections to investigate the prevalence of AR copy number altered PCa within individual selected samples.
We present and apply integrated methodologic steps for interrogating WGS data to characterize the genetic architecture of 10 heart- and blood-related traits in a sample of 1,860 African Americans.
This software interrogated a proprietary database of published data to generate protein interaction networks.
We integrated genomic data from 5 different studies to allow us to interrogate a large number of samples encompassing different types of STS.
At present, if an experimenter wishes to use XFI to interrogate a region of interest within a sample at substantially higher resolution, it may require a different beamline and sometimes even necessitate relocating to a different synchrotron light source.
