Sentence examples for interrogate transcripts from inspiring English sources

The arrays interrogate transcripts across their entire length, which can detect splicing differences between various types of samples [ 22- 24].

We here focus on Affymetrix 3′-expression arrays which use typically 11 to 16 probes per set to interrogate transcripts preferentially near their 3′-end (see Figure 1 for illustration).

Since that time, studies in many species utilizing transcriptome analysis (i.e., DNA chips) to interrogate transcript expression have increased exponentially, and now provide a voluminous amount of data to the scientific community.

DNA array technologies simultaneously measure transcript levels from thousands of genes per sample, and this ability to interrogate transcript levels for an entire genome motivates the interest in toxicogenomics studies.

These studies did not interrogate transcript changes and of course simple deduction of protein from mRNA expression is insufficient because post-translational regulation, small noncoding RNAs, decay differences in mRNA and proteins, and locations or molecular associations of proteins affect overall protein levels [ 52].

Therefore, poor homology along oligo 3' region against interrogating transcripts can be expected to be less influential on hybridization intensity, as confirmed in our data No effect could be detected when selection was made for distance of alignment from 3' side (data not shown).

RNASeqBrowser's individual reads track is also a useful feature for interrogating transcript structures, particulary for chimaeric transcripts and alternative exon usages.

Third, given that highly repeated rRNA genes were omitted from the capture array design, we were able to more comprehensively interrogate the transcripts of interest, which by definition, would allow for better interrogation of low-level transcripts.

Recently, RNA-Seq, a powerful new technique for transcriptome analysis has revolutionized gene expression analyses by providing the ability to simultaneously interrogate all transcripts in an RNA sample (unlike microarrays which are limited to previously annotated transcripts) [ 6].

This point is also illustrated by examination of four probesets on the Xenopus laevis Affymetrix microarray that were designed to interrogate XB transcripts: XlAffx.1.5.S1_at, XlAffx.1.9.S1_at, XlAffx.1.10.S1_at, and XlAffx.1.12.S1_at.1.12.S1_at

Because redundant probe sets may interrogate different transcripts arising from the same gene, examining the consistency of redundant probe sets that are included or excluded from the significant probe set list may expose biologically-interesting features of the data, such as evidence of differential mRNA processing.