Sentence examples for interrogate the genome from inspiring English sources

A primary method for establishing phenotype-genotype links is through Genome-Wide Association Studies (Gwhich whinterrogategathethe genome in regions of common variability and attempt to statistically associate this variability to the phenotype of interest [ 1].

They provide a means by which to interrogate the genome for both common variants of small effect and rarer variants of intermediate/large effects.

We used next-generation sequencing to interrogate the genome of the YLS.

The first wave of techniques involved microarrays specifically built to interrogate the genome with oligonucleotide probes (Borevitz et al. 2003).

Software tools to find these variants deploy different mathematical approaches to interrogate the genome sequences of tumour/germline paired samples.

Ultimately, bioinformatics needs to develop methods that interrogate the genome in the clinic and allow physicians to use personalized medicine in their daily practice.

Three advances allow us to interrogate the genome-wide properties of promoters.

Chromatin immunoprecipitation (ChIP) coupled with high-throughput sequencing (ChIP-Seq) has become the method of choice to interrogate the genome-wide effect of transcription factors.

We used whole-genome and whole-exome sequencing to interrogate the genomes of four subjects with an undiagnosed syndrome.

To account for these strains, we performed composite mapping, which masks the Snhl1 QTL, and interrogated the genome for additional genetic and epistatic interactions.

Interrogating the genome using the triplet method expedites the comparative study of species divergence history and the estimation of genetic parameters associated with speciation.