Sentence examples for interrogate the functional from inspiring English sources
Here, we will summarize the current knowledge of macrophage biology and ECM-mediated differences in mechanotransduction and discuss future opportunities of biomaterials and tissue engineering platforms to interrogate the functional relationship between these parameters and their relevance to cancer.
The methods were designed to preserve the activity of the immobilized protein such that the arrays provide a highly miniaturized platform to simultaneously interrogate the functional activities of thousands of proteins.
Thus, dual perturbation experiments are used to interrogate the functional abilities of cells.
Short hairpin RNA-based and dominant-negative expression-based SHP2 inhibition techniques were used to interrogate the functional importance of SHP2 in BTBC cell biology.
High-throughput model systems must be developed to interrogate the functional consequences of DNA variation and aid in the assessment of pathogenicity.
To interrogate the functional role of APP in cell growth and apoptosis, the effect of APP knockdown in MDA-MB-231 cells were analyzed.
Altogether, our data support a conformational signal-relay cascade during late-stage 60S maturation, involving uL16, Sdo1p, and Efl1p, which interrogates the functional P-site to control the departure of the anti-association factor eIF6.
Together, these results further elucidate the neural circuitry of MI and show that our task robustly and reliably invokes motor imagery, and thus may prove useful for interrogating the functional status of the motor circuitry in patients with motor disorders.
The power of these computational approaches in interrogating the functional mechanisms of transmembrane proteins is illustrated with selected examples of recent experimental and computational studies pursued synergistically in the investigation of secondary active transporters and GPCRs.
The log (p-level) ranked up or down-regulated genes were analyzed interrogating the functional classes of Gene Ontology (GO) [ 102] and compared by the sums of ranked genes (Student's t-test, p < 0.05).
To interrogate the role of ERK in the functional activity of the VEGF promoter, we transfected monocytes with the VEGF wild type construct and inhibited ERK activity with U0126 treatment.
