Sentence examples for interrogate the effects from inspiring English sources

To interrogate the effects of tumor stroma (cancer-associated fibroblasts or CAFs) on epithelia, we created a bioengineered microenvironment using human prostatic tissues.

Our methods can be used to interrogate the effects of buffer conditions, small molecules, and septin-binding proteins on septin filament assembly or stability; determine the effect of alternative septin subunits, mutational alterations, or posttranslational modifications on assembly; and, delineate the location of septin-binding proteins.

We therefore decided to interrogate the effects of one retested compound, amiodarone HCl, on NSCs and their differentiated derivatives.

Thus, we aimed to interrogate the effects of decreasing prenylation on early UUO-induced Ras pathway activation and associated fibrotic responses in the mouse kidney.

Further experiments will optimally generate the full 256-line matrix containing all combinations of alleles between all loci to fully interrogate the effects of all loci in all possible backgrounds.

We were able to interrogate the effects of mixture components and genotypes both independently and in combination, and identify interactions responses among gene families and pathways that ultimately contributed to tolerance differences between individuals.

Thus, the main endeavour of this communication is to interrogate the effect of deformities of cylindrical nanowires on quantum states of electrons in such nanostructures.

HMLEs (HMLE-SNAIL and Kras-HMLE, Kras-HMLE-SNAIL pairs) serve as excellent model system to interrogate the effect of SNAIL targeted agents that reverse epithelial-to-mesenchymal transition (EMT).

The primary objectives of the analysis were to obtain the most precise estimates of the magnitude of the pirfenidone treatment effect in patients with IPF, and to further interrogate the effect of pirfenidone in subpopulations defined on the basis of demographics and baseline measures of disease status.

Consequently, if Arg84Pro and Arg84Gly mutations cause VWS by disrupting the secondary structure of IRF6 leading to a complete loss of IRF6 function, then that change is not detectable in the context of the DNA-binding domain alone; rather, future experiments must be designed to interrogate the effect of altered secondary structure in the context of the whole protein.

We interrogated the effects of tamoxifen on the number of MRUs present in the mammary gland.