Sentence examples for interrogate the effect from inspiring English sources

Thus, the main endeavour of this communication is to interrogate the effect of deformities of cylindrical nanowires on quantum states of electrons in such nanostructures.

HMLEs (HMLE-SNAIL and Kras-HMLE, Kras-HMLE-SNAIL pairs) serve as excellent model system to interrogate the effect of SNAIL targeted agents that reverse epithelial-to-mesenchymal transition (EMT).

The primary objectives of the analysis were to obtain the most precise estimates of the magnitude of the pirfenidone treatment effect in patients with IPF, and to further interrogate the effect of pirfenidone in subpopulations defined on the basis of demographics and baseline measures of disease status.

Consequently, if Arg84Pro and Arg84Gly mutations cause VWS by disrupting the secondary structure of IRF6 leading to a complete loss of IRF6 function, then that change is not detectable in the context of the DNA-binding domain alone; rather, future experiments must be designed to interrogate the effect of altered secondary structure in the context of the whole protein.

We used global hepatic gene expression, from microarrays, and a network-based approach to further interrogate the effect of this locus.

Therefore, to better interrogate the effect of lixisenatide on human beta-cell survival throughout the ~30-day treatment period, we counted total beta- and alpha-cell numbers within the recovered islet grafts.

To interrogate the effects of tumor stroma (cancer-associated fibroblasts or CAFs) on epithelia, we created a bioengineered microenvironment using human prostatic tissues.

Our methods can be used to interrogate the effects of buffer conditions, small molecules, and septin-binding proteins on septin filament assembly or stability; determine the effect of alternative septin subunits, mutational alterations, or posttranslational modifications on assembly; and, delineate the location of septin-binding proteins.

We therefore decided to interrogate the effects of one retested compound, amiodarone HCl, on NSCs and their differentiated derivatives.

Thus, we aimed to interrogate the effects of decreasing prenylation on early UUO-induced Ras pathway activation and associated fibrotic responses in the mouse kidney.

To interrogate the effects of BECN1 and BRCA1 in breast cancer, we studied their mRNA expression patterns in breast cancer patients from two large datasets: The Cancer Genome Atlas (TCGA) (n = 1067) and the Molecular Taxonomy of Breast Cancer International Consortium METABRICC) (n = 1992).