Using this RNAi-compatible OP50 strain and the other bacterial strain HT115, we feed worms different diets while delivering RNAi to interrogate the genetic basis underlying diet-dependent differential modulation of development, metabolism, behavior, and aging.
To interrogate the molecular basis for the differential responses to APR-246, we performed comparative transcriptomic analysis on the three STA-ET-7 cell lines established from the same patient.
As a first step to interrogating the genetic basis of withdrawal behaviour in C. elegans we investigated whether mutants previously reported to affect ethanol dependent behaviours altered responses in the food race paradigm.
We interrogated the evolutionary basis of the low nucleotide diversity observed in Africans by analyzing the re-sequencing panel with tests of natural selection that are based on the proportions of rare and common polymorphisms (i.e. the allelic spectrum) expected under neutrality.
Given the relentless wave of information in the post-genomic era, sleep research in Drosophila will have to overcome significant challenges if it is to continue to be a potent platform for interrogating the genetic basis for sleep and sleep disorders.
Query consists of the ability to interrogate the concept hierarchy on the basis of object associations or, conversely, to reveal object associations amongst selected concepts or classes.
One man lost three fingernails after being detained in Pakistan at the suggestion of MI6 and interrogated on the basis of questions supplied by MI5 and Greater Manchester Police.
Reacting to the increasing numbers of activists being arbitrarily arrested and brutally interrogated on the basis of information illegally taken from them, technical experts have been playing a "cat and mouse" game to combat surveillance against people exercising their freedom of expression and association.
This broad coverage makes it challenging for CTD to accurately design a single-generic query to interrogate the current literature on a routine basis.
Furthermore, in late stages of clinical development, imaging forms the basis of robust response and progression criteria in order to interrogate the drug in a large number of clinical trial subjects.
