Sentence examples for interrogate global from inspiring English sources

Indeed, it has already been successfully applied to interrogate global gene expression patterns in stage I serous invasive versus borderline ovarian tumors [37].

Messenger RNA profiling was performed on custom Agilent maize arrays designed to interrogate global gene expression patterns across circa 105 K probes (Materials and Methods).

Since our data contain experimentally defined PA sites as well as their counts, it provides a unique opportunity to interrogate global 3′ UTR patterning among different tissues.

Still, this study illustrates the potential use of systems biology data from the public domain to further interrogate global 'omics' data.

In order to interrogate global responses to PDGF-BB at both gene and protein levels, we used primary human bladder smooth muscle cells (pBSMC) to perform RNA expression profiling in concert with quantitative analysis of the entire proteome using the SILAC method.

The gain in cumulative protein counts is consistent with earlier reports describing the advantage of interrogating global proteomes using complementary mass spectrometry platforms [21], [27].

In this study, we systematically interrogated global differences in gene expression between nectaries and non-nectary reference tissues, as well as between nectary types and developmental stages.

EM continues to play an important role in interrogating global PSD structure, following the first imaging of the PSD by this method in the 1950s.

In order to assess the relevance of the PDGF/Abl pathway we interrogated global gene transcription data from two publically available global gene transcription data sets from ER+ breast cancer cell lines (ZR-75.1, MDA MB 361 and HCC-1428) thad had been adapted to LTED [ 11, 15].

Prior to further molecular characterization of the PDGF/Abl pathway as a putative mechanism of resistance and potential target for therapy we sought evidence for its likely clinical relevance by interrogating global gene expression data from 81 ER+ patients who received the AI anastrozole as neoadjuvant (pre-surgical) treatment for 14 weeks.

To interrogate the global arrangement of CMs, chromatin marks and TEs, we generated a relational network.