Sentence examples for interrogate changes in the from inspiring English sources

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The promoters with transgenerational differential methylation were analyzed in the online algorithm Repeat Masker in order to interrogate changes in the representation of particular repetitive elements.

High-dimensional flow cytometry, and more recently mass cytometry, have been exploited to interrogate changes in the cellular compositions before and after vaccination [ 10].

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We have constructed an S. ratti cDNA microarray and used it to interrogate changes in gene expression during the free-living phase of the S. ratti life-cycle.

To interrogate changes in structure that give rise to the observed dynamical differences, we measured the chemical shift differences between monomeric Aβ43 and Aβ42.

Finally, using prior knowledge of cognitive dysfunction in this group (O'Muircheartaigh et al., 2011 a ), we interrogate changes in thalamo cortical functional integration from this region of interest to the rest of the brain.

The 500 kHz RF was superimposed on top of low-frequency TEVC (<30 kHz) allowing the RF to continuously interrogate changes in charge displacement mobility during whole-cell depolarization.

Specifically, we interrogated changes in gene expression patterns in MEC cells caused by the knockdown of CRTC1-MAML2 fusion expression.

To understand the signal transduction changes that accompany the cell-death-inducing perturbation of glucose addiction, Graham et al (2012) used a mass spectrometry-based approach to interrogate the changes in the phosphotyrosine proteome that follow glucose deprivation.

Mouse models overcome some key hurdles for biomarker discovery, including technology development [16]; more precise matching of cases and controls to reduce genetic, age, and environmental variables; interrogating the dynamic changes in the plasma proteome through disease progression; and integrating results with the extensive biological knowledge bases [17].

In addition, the technique is capable of interrogating chemical and structural changes in the materials, hence, for the first time, direct correlation can be identified in-situ by means of the same technique.

These initial findings on the transgenerational epigenetic effects of vinclozolin are expanded in the present study by interrogating genome-wide methylation changes in the promoter regions of F3 generation sperm.

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