The random correlation effect to an arbitrary outcome induced by small subset selection from very high dimensional interrelated gene expression profiles leads to an outcome with associated uncertainty.
Previous research suggests that fishing may cause changes to a suite of fish population-level attributes (e.g., survival and recruitment) as well as various interrelated phenotypic expressions at the individual level (e.g., growth, and size and age at maturation; Stokes et al. 1993; Law 2000; Walsh et al. 2006).
These constitutional differences, presumably epigenetic in origin, contribute to about 50% of the observed residual variance which is connected with a network of interrelated changes in gene expression with some genes displaying a decrease or increase in residual variation with age.
These genes share spatial and temporal expression and interrelated functions and are grouped in three related gene families: cornified envelope precursor proteins (involucrin, loricrin, and the small proline-rich proteins [SPRRs]); intermediate filament-associated proteins (profilaggrin and trichohyalin), and calcium binding proteins (the S100As) [reviewed in [ 35]].
Diabetes and obesity are complex, interrelated conditions associated with increased CYP2E1 mRNA expression and/or activity in humans (Aubert et al. 2011; Neafsey et al. 2009).
In this study, several partially interrelated factors affect gene loss, including gene expression levels, number of protein protein interactions, gene dispensability, and rate of sequence evolution (Krylov et al., 2003; Cai and Petrov, 2010).
Other interesting enriched biologic entities among the set of genes with elevated expression (Additional file 8) were the interrelated WNT signaling pathway, cell adhesion, and calcium binding (Additional file 9).
Three key interrelated computational problems arise in the context of transcriptome analysis: gene expression level estimation (GE), isoform expression level estimation (IE), and novel isoform discovery (ID).
To control for all possible interrelated variables, and especially for noisy variables such as expression level is not easy [ 40, 41].
Clearly, the regulation of TF gene expression and function involves a vital network of interrelated processes.
