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Therefore, the obtained results can be the basis of the interpretation of the functional properties of proteins characterizing their activity related to their conformational changes [11].
Since every individual is expected to harbour thousands of variants, many of which may be novel, interpretation of the functional significance of any single variant is critical, and should be undertaken by experienced personnel.
This review focuses on the current understanding of the dystrophin mutations heterogeneity, genotype-phenotype correlations, as well as interpretation of the functional significance of mutations that often require non routine genetic studies.
These experimental results to evidence that the conclusions obtained from the conventional 2D analysis of the stacking of QDs often found in the literature are not reliable and would mislead the interpretation of the functional properties of these nanostructures, being the 3D analysis of the sample as an essential step.
It is essential to elucidate the relationship between blood oxygenation level-dependent (BOLD) signals and neuronal activity for the interpretation of the functional magnetic resonance imaging (fMRI) signals; this relationship has been quantitatively investigated by animal studies measuring evoked potentials as indices of neuronal activity.
Consequently, the annotation of the overlapping genes may directly facilitate an interpretation of the functional association.
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Our findings challenge some of the current interpretations on the functional role of these regions and dispute the hypothesis that small ligands stabilize an inactive state.
Moreover, it should be noted that other interpretations of the functional role of ACC/dMPFC have been developed, such as error likelihood [48], [49], regret [50], action value [51], [52], response evaluation [53], and uncertainty [54], [55], [56].
CM assisted with the statistical interpretations of the functional data.
Some features of Pentecopterus lend themselves to interpretations of the functional morphology and possible mode of life of the eurypterid.
Distinguishing between these interpretations of the functional significance of the vertex potential requires identifying specific criteria for defense behaviors.
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