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The rationale for that was that interpretation of efficacy results of clinical malaria disease collected at health centers would be compromised by the ADI visits and the sample size would be inadequate.
Of course, the lack of a prognostically comparable control group limits the interpretation of efficacy importantly.
main baseline covariates, will be considered as a mandatory part of the primary analysis and a proper interpretation of efficacy.
Interpretation of efficacy in trials of user-dependent HIV prevention strategies requires clear and consistent methods for measuring and reporting adherence to study product.
Although there was a greater improvement in post-teaching MCQ among the simulator group, baseline scores were higher among lecture group which limits interpretation of efficacy.
Pilot experiments must assess tolerability (see above), and pharmacokinetic data (see below) should also be generated to determine whether interpretation of efficacy data is affected by pharmacokinetic interactions (Siim et al, 2003).
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We compared results from MMRM and LOCF_ANCOVA analyses across eight clinical trials of duloxetine in order to investigate how the choice of primary analysis may influence interpretations of efficacy.
Thus, interpretation of the efficacy in the four RCTs without a control group is not straight forward [9 12].
We suggest that this new measure of antigenic distance be used in the design of the annual influenza vaccine and in the interpretation of vaccine efficacy monitoring.
The exact nature of the interaction of vaccine-induced immunity with preexisting immunity and exposure to infection is also not well understood and can affect the interpretation of vaccine efficacy and effectiveness (10).
The intake of antimalarials prior to participating in an in vivo study may alter treatment outcome and affect the interpretation of both efficacy and safety outcomes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com