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Two substructure analysis methodologies were implemented, as described in the section "Interpretation of Compound Substructures".
The contribution of chemical substructures to bioactivity on human cyclooxygenases was deconvoluted using a predictive and a Student's method (Figure 2): Figure 2 Interpretation of compound substructures.
It is shown how such "local pragmatics" problems as reference resolution, the interpretation of compound nominals, the resolution of syntactic ambiguity and metonymy, and schema recognition can be solved in this manner.
However, as mentioned above they often do not have a controlled ratio or mass of the different cell types, which can confound the accurate interpretation of compound effects.
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In doing so, the XRF analysis was always carried out first to classify the elements present in the areas of interest and give preliminary information for the interpretation of the compound specific data to be gained in the complementary analyses [14, 15].
However, alignment of the spectra aids in the interpretation of individual compounds by improving the quality of the pattern recognition analysis.
This study presents a multiphase flow and multispecies reactive transport model for the simultaneous simulation of NAPL and groundwater flow, dissolution, and reactive transport with isotope fractionation, which can be used for better interpretation of NAPL-involved Compound Specific Isotope Analysis in 3D heterogeneous hydrogeologic systems.
MA carried out the interpretation of the isolated compound.
Correlation of different images allowed for fast and easy interpretation of the drug compound distribution, and areas of accumulation could be directly linked to certain tissue regions.
MJ carried out procurement, extraction, study, drafting and isolation work along with AA, MA has made study design, supervise, interpretation of the isolated compound and revision of the manuscript.
A number of PI3Kγ kinase inhibitors have been shown to block T-cell functions but interpretation of PI3Kγ biology from compound effects is limited by the target selectivity of compounds 13.
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