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In addition, decision tree-based methods facilitate the identification and interpretation of complex interactions among predictor variables [ 32, 33].
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Interpretation of associations with individual metals was limited by interrelated issues, such as covariation among pollutants, the possibility of complex interactions among pollutants, and power constraints (Tolbert et al. 2007).
Finally, taking into account that the interpretation of multiple indices is not clearly established, further studies should comprehensively analyse the application of DTI indices to the understanding of complex interactions between vascular disease and degeneration.
Almost all inherited features or traits are the products of complex interactions of numerous genes.
Measuring CIMT, as a surrogate marker of cardiovascular disease, is widely used and validated method in both patients with or without T2DM to detect subclinical atherosclerosis, however to predict the relative risk for the development of future cardiovascular diseases is much more difficult and presumes holistic interpretation of the complex interactions between both genetic and clinical factors.
Open image in new window Fig. 1 Interpretation of complex object roles and complex concepts.
Open image in new window Fig. 1 Interpretation of complex concepts.
This requires analysis focussing on interactions and relationships at higher organisational levels, and also investigation teams with basic competence in safety science and the interpretation of complex systems.
However, interpretation of experimental data is hindered by the multitude of signaling molecules and complex interactions of the pathway.
Overall, GIENA is systematic approach for the identification of dysregulated interactions at the pathway level and provides specific guidance for interpretation of disease-specific interactions in complex diseases.
The complex interactions of affected brain circuits are too diverse across disabilities to generalize result interpretations from one to the other.
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