Computational strategies are therefore needed to help interpret the consequences of gene essentiality data on gene activities.
In parallel, genetic variance, accuracy of selection, inbreeding and loss of favourable alleles over generations were also studied, which helped to interpret the consequences of the different strategies.
An example is Dr Punglia and coworkers' editorial in the New England Journal of Medicine, which engages in a comprehensive analysis to interpret the consequences of local control on breast cancer survival [ 2].
In general, the final semester students in this study were able to define pharmacological concepts, but showed less ability to discuss the meaning of the concepts in depth and to interpret the consequences of the given information in a clinical context.
In the process of developing a new concept of self in order to positively interpret the consequences of disability [5,8,9], Corbin and Strauss [17] demonstrated that some people not only reach the 'stage' of acceptance, but also go on to a state of 'transcendence'transcendence
We transfected the HEY and OVCAR8 ovarian cancer cell lines with CCL2 cloned into pcDNA3.1, but were unable to develop stable clones with comparable levels of expression to the HOSE cells, and so were unable or to interpret the consequences of in vitro or in vivo assays (data not shown).
RNA-seq could be used to provide a comprehensive view of the differences in transcription between normal and diseased samples but also to correlate alterations in structure and copy number that may affect gene expression, thereby helping to interpret the consequences of mutations in gene control regions.
Combining these data with additional functional information allows us to interpret the consequences of RNA binding in diverse cellular processes, including alternative splicing, 3′ end processing, and translation (Darnell et al., 2011; Hafner et al., 2010; König et al., 2010, 2012; Licatalosi et al., 2008; Ule et al., 2003; Wang et al., 2012).
Prediction of correlated response is important in breeding program design and in interpreting the consequences of natural selection.
Bond cleavage can generate deleterious pores, but may also be required for the incorporation of new material and for the expansion of the wall, highlighting the importance of mechanical forces in interpreting the consequences of hydrolysis in models of growth.
