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It is not clear how how an investigator should interpret redundant probe sets that generate discordant results, which is one of the problems we address in this paper.
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An enhanced phenotype in the double mutants compared to the compound single mutants is often interpreted as "redundant activities".
As indicated in Methods, the KWII-based definition of interaction yields results that difficult to interpret for completely redundant variables because in the presence of an even number of completely redundant variables, the KWII is positive.
Similar to the pH effects, we did not observed altered lipid effects in WT verses KO cells, which can be interpreted as a redundant effect or lack of lipid effect through OGR1 in these cells.
We interpret this as genes with redundant signaling functions.
The operational definition can yield results that are difficult to interpret in the presence of variables that are completely redundant with each other because an even number of completely redundant variables will result in a positive KWII.
The phenotype of embryos with severe developmental defects due to loss of redundant gene functions can be difficult to interpret.
Searches against NR sequences are faster and more sensitive than the equivalent searches against redundant libraries, and the search results are easier to interpret.
In addition these tools output lists of often redundant or too specific GO terms, which are difficult to interpret in the context of the biological question investigated by the user.
Collectively, we interpret these results to indicate that demethylated PP2A plays essential non-redundant functions that cannot be undertaken by the methylated pool of this protein.
Results are interpreted in two ways: redundant frames with the playground size and the same with node densities.
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