We expect that combinations and individual contribution of regulatory factors and circuits are different under in vitro and in vivo settings; however, their interplay results in the formation of comparable CCSs.
Between these cells, the uncoordinated interplay results in the formation of typical non-caseating granulomas.
Depending on the outcome of interest, this interplay results in either a J-shaped or inverted J-shaped dose response (sometimes called "U-shaped" or "inverted U-shaped," or "biphasic" or "β-curve").
We first define gene sets of our interest and introduce some existing findings about the main factors based on the ChIP-seq data, and then present their interplay results to motivate our hypothesis of existence of cofactors and further analyses.
The analyses of cellular behavior after this interplay resulted in dramatic changes in gene expression and levels of proteins involved in the main steps of the angiogenic process, including the upregulation of profibrotic and extracellular matrix molecules.
Therefore, disruption of the cooperative interplay resulting from partial down-regulation of MyD88 signaling in B cells and kidney cells would act to break the persistent cycle of inflammation and vascular permeability resulting in kidney damage in SLE without fully immunosuppressing the host.
In the long run, this mutual close interplay can result in co-evolution of host and pathogen.
In this comfortable and heritage-conscious community, the interplay has resulted in plans for a shopping center that takes its design inspiration, its developers say, from some nearby and well-loved barns.
The science/management interplay ultimately resulted in surface water allocation strategies that are balances to society and the affected natural environment.
When repeated stimulus exposure is combined with a training task, the resultant interplay of neurons could result in coincident changes in P2 and perception.
