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This interplay requires crossover interference: it is absent in a fancm zip4 background where crossovers occur but interference is absent.
The understanding of this combinatorial interplay requires a paradigm shift from single key players to the coupled activity of many regulatory control elements.
There is a reciprocal interplay in which COs are decreased in HOM regions and increased in HET regions and this interplay requires interference.
Thus, unlike dMSNs, where ERK activation upon D1 and GLU receptor interplay requires Ras-GRF1, 23 in cholinergic cells the route of activation may be distinct and the underlying mechanisms are yet to be elucidated.
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Since the suppressive interaction between salicylate and chloramphenicol is partially associated with the synthesis of AcrAB-TolC efflux pumps, we also hypothesized that cells with constitutive mar promoter activity would disrupt the cost-benefit interplay required for drug suppression.
Deep understanding of the processing-structure-properties interplays requires multiple characterization techniques to provide insights on the impact of the processing/compatibilization on morphology and phases' distribution.
We also found that, while Sirt4-ANT2 interplay was required for ATP homeostasis, ANT1 did not seem to play a role in Sirt4-dependent changes.
As it was previously shown that cytoplasmic loop-loop interplay is required for MLO function [ 38], we anticipated that such rather big deletions in one of the cytoplasmic loops, if the protein should properly fold at all, would lead to loss-of-function of the protein.
It requires interplay between several factors.
Maintenance of optimal heat-shock resistance clearly requires interplay of systems/functions dependent on many specific transcription factors.
We believe developing a reflective equilibrium requires interplay of actual judgements of specific issues and moral theory or normative considerations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com