These effects vary across regions of different endemicity and are highly correlated with the interplay between the timing of interventions in age and the age dependent risk of acquiring an infection.
The early goal-directed therapy protocol involved a complex interplay of a variety of interventions, including volume resuscitation, central venous saturation monitoring, red cell transfusions and inotropic therapy.
As such, communication is one part of the interplay and interventions that focus solely on communication, may lose sight of other factors and/or the interrelationship among factors.
Created as a site-specific installation responding to the particular architectural environment of the ancient forest, the project aims to "expose an ecosystem of dynamic natural and unnatural interventions: the interplay of man and nature moderated by technology over the centuries".
The development of structured tools for assessing implementation processes, which take account of this complex interplay between interventions, individual actions, and context, would represent an advance in applying theory to understand and address implementation problems in practice.
However, deciding among them or determining the most appropriate level of investments in them presents a significant challenge for decision-makers, as there is uncertainty around predicting the effects of interventions over time or the interplay between them [ 17].
The RCT will also assess the physical and psychosocial effects of the intervention and the complex interplay of factors that influence the effectiveness of the intervention.
Yet, the interplay between patient characteristics, self-management capacity, and the likelihood for success of interventions is still unclear.
Although empirical and theoretical understanding of processes of implementation in health care is advancing, translation of theory into structured measures that capture the complex interplay between interventions, individuals and context remain limited.
In this research supplement, the ICEMRs attempt to provide a comprehensive view of the interplay between control interventions and epidemiology, vector ecology, parasite diversity, insecticide and drug resistance, pathogenesis, diagnostic performance, molecular epidemiology, biosignatures of transmission and immunity, and urban malaria across different settings.
