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The multiple interplay of components of the classical and alternative complement pathway in association with the activated immune system provide a possible mechanistic link between photoreceptor-degeneration induced upregulation of CD74 activation in microglia and secondary vasoregression, but the causal relationship between complement activation and vasoregression needs further substantiation.
SR proteins are important regulatory splicing factors and facilitate the correct interplay of components of the splicing machinery.
The assembly of chromatin is mediated by an interplay of components of the DNA replication machinery and histone chaperones, which mediate the deposition of histones into nucleosomes (Alabert and Groth, 2012; Annunziato, 2012).
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This assay reflects the interplay of all components in the fibrinolytic system with the exception of the activators that are in excess.
The different trends of the net carbon change are mostly explained by the interplay of two components: emissions from logging damage and accumulation from recovery in logging gaps.
The ability to deposit thin films onto glass at ever increasing deposition speeds and greater precision relies on a complex interplay of technological components.
Circulating levels of vitamin A (retinol), retinyl esters, or RA do not necessarily reflect the retinoid status of target cells, since activation of RA signaling depends on a complex interplay of the components of this pathway, including the presence of RA-synthesizing enzymes, RA receptors (RAR, RXR), co-activators/co-repressors, and RA-metabolizing enzymes.
These data may help to understand the complex interplay of the components of the mouse pre-RC and should allow us to refine its structural architecture as well as its assembly in real time.
Hence, the outcome of Rsd-dependent regulation is determined by an orchestrated interplay of numerous components involved in the transcription reaction.
Gene expression as governed by the interplay of the components of regulatory networks is indeed one of the most complex fundamental processes in biological systems.
Lupus, like all common human disorders, results from the interplay of these components.
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CEO of Professional Science Editing for Scientists @ prosciediting.com