These findings illustrate the complex interplay of bio-active dietary factors, gender, tissue sub-site, and endocrine status in intestinal carcinogenesis and neoplasia.
8 The sophisticated interplay of the multiple active-site residues involved, including for example, the charge relay system of the catalytic triad, 7c suggests that any deviation from such a highly efficient arrangement is likely to be penalised.
This is particularly remarkable since cell division involves drastic shape changes that are mechanically induced by the active interplay of multiple cytoskeleton modules.
Fourth, the overall transport success of large cargos appears to be more sensitive to RanGTP levels than other cargos (Lyman et al., 2002; Snow et al., 2013) and thus RanGTP somehow influences the interplay of cargo size and active transport.
Incorporating these findings with previous data, we propose that the dynamic interplay of residues on either side of the active site acts to correctly position the substrate for nucleophilic attack.
Geomorphology has long been recognised as a key to evaluate the interplay between tectonics and landscape geometry in the regions of active deformation.
Secondly, the degree of roughness is linked to a specific distribution of active dissolution sites, and the resulting interplay between morphology and kinetics carries with it a local segregation of reactants and the detachment of clusters of varying size.
The phosphorylation of the PolII CTD and the methylation of H3K4 are probably the best markers of active transcription, but it is unclear how their interplay is regulated to affect gene expression.
Etournay Popović, Merkel, Nandi et al. also present a theoretical model that describes how the interplay between active force generation and the response of cells to the resulting tension shapes the wings of fruit flies.
We conceive the world both as a community of active spirits, willing and representing, and as an aggregate of objects in mechanical interplay and shift perspectives as needed.
