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Our data demonstrate that the RhoA/ROCK1 signalling pathway has important roles in the determination of cell fates and the modulation of Erk1/2 activity at the Mek Erk interplay level.
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Complexity stems from the interplay among levels of biological organization as energy and matter is integrated into larger units that superimpose onto the smaller parts.
However, we are still interested in the interplay between high-level and low-level states only.
The sustained importance of theory in all levels of learning suggests an interplay between low-level learning from videos, progressing through repetition, several engagement opportunities and application (deep learning) in the seminars.
The sequence architecture is controlled by an interplay between lake level changes and sediment supply.
On a longer term, the interplay between sea level changes modulated by 100-ka cycles and regional subsidence controls the stratigraphic architecture and the growth pattern of the continental margin.
Multiple successions of buried fluvial channel systems were identified in the Quaternary section of the mid-shelf region of the northern South China Sea, providing a new case study for understanding the interplay between sea level variations and climate change.
More research is warranted to address the interplay between the level of HSC engraftment and the resulting induction of specific immune responses versus tolerance.
Thus there is a dynamic interplay between the level of the trait, the expression of behaviour and variation in context.
Some drugs, including IMiDs, bisphosphonate, and cyclophosphamide, can interplay at this level, but use of drugs able of triggering this signaling is an urgent need to improve the efficacy of current treatments.
These questions are deeply complicated by – and may also be critical to – the ongoing discussion of the various levels at which natural selection operates, and the interplay between these levels.
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