Translation initiation in eukaryotes requires the interplay of at least 10 initiation factors that interact at the different steps of this phase of gene expression.
It results from a harmonious interplay of at least three natural conditions: the region's latitude is far enough south to dissipate the most severe North Pacific winter storms, a cooling layer of marine air moderates the summer sun, and the tall mountain ranges shield the region from potentially intense blasts of desert heat and cold.
They both theorise that human behaviour is based on an interplay of at least two biological self-regulatory systems – one which is responsive to aversive stimuli (BIS or HA) and the other to appetitive stimuli (BAS or NS).
RA is an extremely complex disease, with an etiology involving the interplay of (at least) genetic predisposition, environmental factors, and immunity to self molecules made immunogenic by posttranslational modification [ 33].
Current evidence in medial PFC indicates that such interplay occurs at least with the acetylcholine nicotinic receptors expressed in the thalamocortical fibers (Lambe and Aghajanian 2003) and with the serotonergic inputs onto pyramidal cells (Liu and Aghajanian 2008).
DNA methylation patterns are known to be established and modified in response to environmental factors by a complex interplay of at least three independent DNA methyltransferases, DNMT1, DNMT3A and DNMT3B [ 24]-hence making DNA methylation a prime candidate for linking environmental cues and disease.
The existence of a universal, nonmonotonic dependence between gene compactness and expression level seems to suggest that gene architecture depends on the interplay of several factors at least some of which are selective.
This typically requires a rather intricate interplay of different selective pressures, at least, if the divergence of mating preferences has to be accompanied by a simultaneous divergence of male ornaments to generate reproductive isolation.
The present data on thalamic connections with the auditory cortex, area 5, and premotor cortex support the notion of early multimodal interplay involving the thalamus, based at least on 4 possible mechanisms.
Mathematical expressions, in particular the sensitivity analyses of dimensionless numbers (e.g., Damkohler number, Thiele Modulus, Peclet number), can be effective to clarify at least the interplay of mass transfer and biodegradation kinetics.
