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However, internet trials often have missing data.
The main methodological limitation of Internet trials is high rates of loss to follow-up [10].
Findings thus appear to support ongoing development of Internet trials and methodological research to improve them.
Internet trials / future research Conducting research on the internet is a fairly recent development in medical research.
Each of our six categories was a quality or characteristic of internet trials; each had a positive and negative dimension.
The results of this study provide researchers with an insight into the participants' perspectives on Internet trials.
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Before start, the study was registered in a public Internet trial archive (Current Controlled Trials Ltd ,ISRCTN01559032).
Before start, the study was registered in a public internet trial archive (ISRCTN46272088).
On randomisation, the clinical unit's internet trial system issued a unique participant identification number and the participant was randomised to one or both trials according to eligibility.
It will be the first Internet trial for any mental disorder that simultaneously investigates the role of human and automated support and which goes beyond research directed at effectiveness--although this is also a goal--to research focusing on process variables, such as predictors of adherence and of non-response.
In Internet-based trials, the Internet is used for recruitment of trial participants, delivery of the health intervention, and/or data collection [ 3- 5].
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