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With an internal display you can also internalize power, control and storage, and optical qualities are adjustable on the fly (though they shouldn't need to be changed much after an initial calibration).
In agreement with previously reported results [13], the plasmid-cured avirulent Y. pseudotuberculosis strain YPIII was efficiently internalized by control HeLa cells (69% internalization) (Figure 3B), whereas the corresponding wild-type strain remained largely extracellular (11% internalization) (Figure 3B).
Hence, the most dramatic inhibition of EGFR internalization occurred at 2 min with 60% being internalized in control cells compared with 20% being internalized in cells expressing Tom1L1/Y460F, Tom1L1/Y392F or Tom1L1/Y460F SH3.
Upon 15 min of stimulation, small patches of aggregated receptors are formed in both MβCD untreated and treated cells, indicating that lateral mobility is not affected by cholesterol depletion; however, after 30 min of stimulation the engaged receptors mainly remained at the cell surface in the presence of the drug, while the majority of them internalized in control cells.
This effect was not as evident after 30 min with fMLP, where the differences in the amount of receptor internalized in control and GIT-depleted cells became non-significant.
In contrast, clear intracellular staining was not visualized with the non-internalizing control antibody (human myeloma IgM).
We found that an increase in internalizing problems among the family-bereaved as well as in the non-bereaved group is predicted by the amount of pre (loss) internalizing problems, after controlling for gender and SES.
When comparing cases and controls with internalizing problems only (group 1) to cases and controls with none (group 4), it was clear that teachers had a tendency to exclude students with only internalizing problems from the referral lists, showing that these problems often went unnoticed (p = 0.090).
Indeed, about 20% of surface PrPC was internalized in both control and cholesterol depleted cells (Figure 1C, D and E, F).
Sixth grade levels of control variables and internalizing and externalizing factors were entered in the first hierarchical step of the logistic regression.
Consequently, through the use of cross-lagged path analysis in a longitudinal sample of adolescents with diabetes, the present study examined how coping and psychological symptoms (both internalizing and externalizing) influenced glycemic control across time.
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Justyna Jupowicz-Kozak
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