Macrophages constitutively internalize a wide range of complex glycoproteins, proteoglycans, and glycosaminoglycans that are degraded by lysosomal glycosidases to generate free sugars or oligosaccharides.
Although S. aureus is primarily an extracellular pathogen, there is strong evidence that it can be internalized by a wide range of human host cells.
Prior research has shown that internalizing behavioral problems may lead to a wide range of learning deficits in areas ranging from problem-solving tasks to verbal memory to intellectual function (Emerson et al. 2005; Gunther et al. 2004; Lundy et al. 2010).
We demonstrate that siRNA-carrying dendriworms can be readily internalized by cells and enable endosomal escape across a wide range of loading doses, whereas dendrimers or nanoworms alone are inefficient.
Studies of children with parents with ASPD are rare because of the parents' often uncooperative attitude toward service providers and investigators, yet the few studies available in the literature show that the offspring of parents with ASPD, like children of those with BPD, exhibit a wide range of psychiatric disorders, both internalizing and externalizing [ 19- 22].
The CBCL is a commonly employed parental measure of youth symptoms, assessing a wide range of problems, and featuring Internalizing, Externalizing, and Total Scales.
It was recently found that CTX not only binds a wide range of tumor cell types but is also internalized by proliferating human vascular endothelial cells [ 23].
The 2016 Cyber Media Roundtable covered a wide range of complex topics, and the engagement of participants signaled strong interest in internalizing the material.
