Sentence examples for internalized upon from inspiring English sources

Second, the ADC-directing antibody must be rapidly internalized upon ligation to its targeted receptor.

Alternatively, CD38 may be internalized upon stimulation [16].

The Flag-tagged CysLT1R was not internalized upon stimulation in cells over expressing the DN-Eps-15 construct (Fig. 5B).

Interestingly, however, syndecan-4 was not internalized upon the addition of the KKDC peptide but rather appeared clustered on the cell surface (Fig. 2, upper panels, KKDC).

We observed that IGF1R is internalized upon ligand binding in ES cells and that this process is dependent on clathrin or CAV1.

In porcine kidney cells, (-IRE -DMT1 isoforms have been shown to be more rapidly and efficiently internalized upon metal exposure when compared to (+IRE -DMT1 isoforms [39].

These include stability of the antibody fragment, the labeling chemistry (direct or indirect), whether critical residues are modified, the number of antigen expressed on the cell, and whether the target has a rapid recycling rate or internalizes upon binding.

Cells expressing ΔCXCR7 showed a marginal loss of primary antibody from the cells surface over time, in accordance with the notion that ΔCXCR7 does not internalize upon ligand exposure [5] and the failure of mediating CXCL12 degradation (Figure 3D).

CD20 is not shed from the cell surface and does not internalize upon antibody binding [ 6].

We finally examined whether MOR-mcherry internalizes upon agonist treatment, as largely described for MOR expressed in transfected cells (Borgland et al. 2003) or neurons (Arttamangkul et al. 2008; Haberstock-Debic et al. 2005).

As expected from the biological characteristics including the expression pattern and the potential to internalize upon binding PCa cells, the Ga-labelled PSMA inhibitor Glu-NH-CO-NH-Lys(Ahx -HBED-CC shows high Ahx -HBED-CC in smAhx -HBED-CCeshows is cleared rapidly from background tissue.