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It has been argued that the exigencies of communal life require agreed codes of behaviour, which become internalized in the process of socialization as moral laws; and the natural affection that develops among humans produces the more occasional sense of a call to heroic self-sacrifice on behalf of others.
Although TLRs are not phagocytic receptors per se, they are also internalized in the process and participate in the link between phagocytosis and inflammatory responses by triggering the production of cytokines [ 76].
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These peptides are internalized in the cells by an active process of endocytosis and can traverse the intestinal mucosa with different kinetics and immunological effects.
The gut usually forms from a population of cells that are localized at one point of the early embryo and that get internalized in a process called gastrulation [ 7].
At the endosomal membrane the activated RTKs are sorted and internalized in intralumenal vesicles, processes that end their signaling activity and generate multivesicular bodies.
Tf is a transport protein that is considered as a potential drug carrier, because of its unique ability to be internalized by cells in the process of endocytosis and cross physiological barriers in the process of transcytosis; several Tf-based therapeutics are currently in development.
We examined primary rat adipocytes by subcellular fractionation to examine if the insulin receptor was internalized in a caveolae-mediated process.
We showed that PGN-Bio was bound to the cell surface and internalized in an endocytosis-like process (Fig 8) as has recently been described with HEK293T as a model system [55].
As a critical member of the low-density lipoprotein (LDL) receptor family, LRP5 may bind and internalize ligands in the process of receptor-mediated endocytosis and also play a crucial role in skeletal homeostasis [ 32, 36].
IpaB channels, specific for small monovalent cations, are internalized in a dynamin-dependent process (III).
The requirement for Environmental Impact Statements prompted numerous complaints at the time, but today, we've internalized the process.
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