The effect of introducing an antibody is to reduce the internalized toxin concentration to a value T i ≤ T i.
However, of particular interest was the observation that different internalized system L substrates led to different internal concentrations of l-serine at equilibrium.
While estrogen receptors are saturated at the ligand concentrations available in the follicle, ligand-bound LH-receptors are rapidly internalized, and the concentration of ligand-bound LH-receptors is therefore much lower than the total LH-receptor concentration.
It is evident that the two main effects described above (reduction of the concentration of internalized toxin at a given time and increase in the time required for the internalized toxin to reach a given concentration) are not independent of each other.
Pit and LDL concentrations are determined by the same 9 parameters except for the rate of LDL degradation to cholesterol (k id ) which not surprisingly, decreases the concentration of internalized LDL.
The process of toxin internalization is phenomenologically introduced into our model by the following equation: (4) d T i d t = k 3 C R, where T i is the concentration of internalized toxin.
Since changes in z0 can be described comprehensively by means of the parameter Ψ, it still remains the only parameter needed to characterize the influence of an antibody on the concentration of internalized toxin (25), (27).
This can be related, in accordance with (23) and (26), to a corresponding decrease in the concentration of internalized toxin T i and a consequent increase in the toxin internalization time (since it takes longer to achieve a give level of T i ).
A predation and transport conceptual model was developed to extrapolate these results to environmental conditions of typical (oo cyst concentrations in surface water in order to predict concentrations of internalized (oo cysts in filtered water.
Decontamination efficiency of different food disinfectants at different concentrations against internalized Salmonella spp. has been evaluated.
