Sentence examples for internalization with from inspiring English sources
We found that in cells with decreased RACK1 expression levels there is an increase in the extent of M2 internalization with over 60% of receptors internalized after 30 minutes compared to almost 45% of receptors internalized in cells with normal levels of RACK1 expression (Fig. 5).
Thus, we sought to correlate this phenomenon of decreased internalization with the various hypoxia-induced cellular adaptations that have been published so far.
The aim of this study was to design thiolated surface stabilized superparamagnetic iron oxide nanoparticles (TSS-SPIONs) for efficient internalization with high MRI sensitivity.
The aim of this research was to prepare and assess in vitro and in vivo uptake kinetics in cancer cells of 99mTc-Tat-BN and to compare its cellular internalization with that of 99mTc-BN.
Abrogation of β-arrestin ubiquitination, either by expression in Mdm2-null cells or by dominant-negative forms of Mdm2 lacking E3 ligase activity, inhibited receptor internalization with marginal effects on receptor degradation.
Surfactants are commonly used drug carriers, however, there is a lack of understanding regarding the relationship between drug loading, drug release kinetics, and cell internalization with the physicochemical properties of the drug carriers, preventing rational design.
Epidermal growth factor containing endosomes were labeled at 30 min post-internalization with lysotracker, which detects acidic compartments.
We have thus derived an ultrasensitive response of CIE-internalization with respect to EGF-stimulation, without assuming any discriminative receptor modifications.
By contrast, CXCR4 becomes permanently down-regulated following stimulation with CXCL12 and its internalization proceeds with a minimal degradation of the chemokine.
These results suggest that SPARC is internalized through a SPARC-specific pathway and that its internalization increases with age.
This is consistent with our in vitro assays showing MM07 causes reduced internalization compared with [Pyr]apelin-13.
