Sentence examples for internalization ratio from inspiring English sources
Among those PSMA-1007 showed an outstandingly high internalization ratio of about 70%% while the K i was in the typical range (6 nM).
Our new approach to use parameter dependence analysis in experimental design reveals that measurements of HER3 phosphorylation and HER2 internalization ratio may prove to be especially useful for the estimation of critical model parameters.
The average relative internalization ratio among these strains was 74% (±31%).
The structure appeared within 12 h, and further incubation resulted in its growth into a large cellular aggregate due to reiterative internalization, which hampered the accurate enumeration of internalization ratio after 24 h.
Discussion/conclusion: Based on our experience with PSMA-617 and preliminary results we developed a series of radiofluorinated PSMA inhibitors with high affinities and internalization ratios.
Results: All 18F-labeled PSMA-inhibitors presented in this study showed low nanomolar affinities towards PSMA, usually paired with high internalization ratios of more than 15%%, shown in vitro.
Despite no evidence of nanoparticle internalization, the ratio of reduced glutathione levels (GSH) relative to the oxidized glutathione (GSSG) in plants decreased when plants were exposed to QD dispersions containing humic acids, suggesting that QDs caused oxidative stress on the plant at this condition.
Increasing the concentration beyond 20 μg/ml did not increase the QD internalization, but the ratio of cell death began to rise (Fig. 7).
To explore the tunability of our platform, surface density of targeting ligand was varied; our results indicated that the internalization rate varied with the ligand-to-polyplex ratio in a "switch mode" fashion.
In general, the ratio of internalization spores vs. attached spores under our assay conditions is approximately 1∶10 1∶5.
As determined by titration of peptide, 50 nM of H1299.3 fluorescence conjugate resulted in sufficient signal-to-noise ratio for detecting internalization by the flow cytometry assay and thus this concentration is used for subsequent internalization assays.
