Sentence examples for internalization property from inspiring English sources
Second, the internalization property of LXY30 on α3β1 integrin-expressing cancer cells could be used to facilitate delivery of conventional chemotherapeutic agents, target-specific agents, siRNAs, and microRNAs into tumor cells, either through direct conjugation or by encapsulation inside LXY30-decorated nanocarriers.
Computational modeling based on the temporal activation profiles enabled us to not only rediscover already-known protein interactions with Y992 and internalization property of mutated EGFR but also further gain model-driven insights into the effect of cellular content and the regulation of EGFR degradation.
Species specificity, antigen specificity and internalization properties were first assessed in vitro.
The internalization properties of the radiopeptides [111In]AT1S and [111In]AT2S were studied in rsst2A + AR4-2J cells at 37 °C with or without excess Tate.
CPPs such as MAP exhibit unique internalization properties which enable them to deliver attached bioactive molecules, including proteins and peptides, into the cytosolic or nuclear compartment of cells.
Compared to the CCK2R-targeted peptide probe dQ-MG-754 [20], we detected no differences in binding and internalization properties of the probes QE and bivQ at 37°C (Figure 2f).
In this study, we constructed two CD81 chimeras by linking the cytoplasmic domains of recycling surface receptors, low-density lipoprotein receptor (LDLR), and transferrin receptor (TfR), respectively, to CD81 and compared their internalization properties to wild-type CD81.
In this study, we describe the use of penton-dodecahedron (Pt-Dd) VLPs from human adenovirus type 3 (as3) as cancer vaccine vehicle for specific antigens, based on its unique cellular internalization properties.
Here we report the generation of two MC4R-based RASSLs and their properties with respect to their constitutive activities, the potencies of endogenous and synthetic ligands, and their internalization properties.
In GBM, mutant EGFRvIII is always present at the cell membrane due to its defective internalization properties [ 44].
In addition, THIOMABs were shown to retain internalization properties, suggesting that antibody sulfone conjugates should also be suitable for ADC applications.
