Sentence examples for internalization ability from inspiring English sources

Besides, cytotoxicity and cell internalization ability were established on J774 murine macrophage cell line.

The antibody can be efficient in cell uptake of the carrier system and nanoparticles thorough the internalization ability of Anti-HER-2 (Moore and Cobleigh 2007; Wuang et al. 2008).

The internalization ability of CPP and cytotoxicity of saporin were therefore successfully integrated in the C-SA-Y nanogel, with both properties working cooperatively to yield a cytotoxic C-SA-Y nanogel.

The A54 PEG CS SA micelles presented special internalization ability into human hepatoma cells BEL-74022) when the cells were co-incubated with normal liver cells in vitro, and high distribution ability to liver and hepatoma tissue in vivo.

Therefore, testing the internalization ability and functional activity of the whole Oct4 protein in various cell types was a consequent step.

To explore the importance of receptor regulation, we engineered a series of Gi-coupled receptors that differ in signal length, degree of agonist-induced internalization, and ability to induce adenylyl cyclase superactivation.

The potential utility and appeal of this peptide-guided gene delivery lies with its internalization, the ability to control the nature of its constituent parts, and ease of generation.

In the present study, we investigated ErbB2 internalization-inducing ability of non-competitive anti-ErbB2 mAb combinations and surprisingly found that most of the mAb combinations tested did not down-regulate ErbB2.

Thus, with enhanced internalization and targeting ability of PEG conjugate of NAG DOX has implication in targeted anticancer therapy.

Confocal laser scanning microscopy (CLSM) and flow cytometry (FCM) results showed that the NAG targeting moiety enhanced the internalization and targeting ability of NAG-P(St-alt-MA 58-b-PSt130 nanoparticleSt-alt-MA 58-b-PSt130

Smart nanoscale drug delivery systems combine the advantage of the small size, to achieve passive targeting capacity and enhanced cell internalization, with the ability to undergo morphological or chemical changes in response to the target-site microenvironment, leading to accelerated release in the disease milieu.