Previously, we have shown that a sigma-2 fluorescent probe, SW120, which is an analogue of SW 43, is internalised into cells through endocytotic mechanisms and distributed in mitochondria, endoplasm reticulum and lysosome (Zeng et al, 2011).
The big Wall Street firms have lately made great efforts to internalise trading through electronic alternative-trading systems, commonly known as ATSs.
After deposition within the lung, alveolar macrophages (AMs), tissue resident macrophages that will remove microorganisms and other particulates, will be the first cells to encounter the cryptococci and will respond by internalising them through phagocytosis (Goldman et al., 2001).
16 Oligoarginines were reported to be internalised into mammalian cells through an endocytotic pathway, mediated by binding to cell surface heparan sulfates linked to proteoglycans, 17 followed by back-transport into the Golgi complex and endoplasmic reticulum.
This principle was justified by the idea that a judge, through his professional training, internalised what Alan Cromartie, a political historian and theorist, referred to as "an infinity of wisdom", something that mere politicians or laypersons could not understand due to the complexity of the law.
Her friend, the novelist Lisa Appignanesi, says: "The Poles, like the British, have internalised an ideal aristocracy and this comes through very clearly in Eva's work.
While previous studies have clearly identified mechanisms through which S. aureus can become internalised into osteoblasts, thus evading the immune system and avoiding antibiotic attack, these studies failed to identify mechanisms that lead to bone destruction.
The complex of EphA2 and Cbl is then internalised into early endosomes, where EphA2 is subsequently degraded through proteosomal and lysosomal pathways.
