Sentence examples for internal influenza from inspiring English sources

As a possible alternative, vaccines directed at T cell epitope domains of internal influenza proteins, that are less susceptible to antigenic variation, have been investigated.

The presence of characteristic sites in eight of the nine internal influenza proteins indicates that host adaptation is highly complex and systemic in nature, requiring the participation of products from the whole genomic ensemble.

Specifically, cell-mediated responses typically focus on peptides from internal influenza proteins, which are far less susceptible to antigenic variation.

We can also develop fused DNA vaccine with internal influenza protein or other proteins that induce cellular immune response that does not seem to contribute to preventing infection.

MVA-NP+M1 is a modified vaccinia virus Ankara (MVA) vector (replication-deficient) expressing the conserved internal influenza antigens nucleoprotein (NP) and matrix protein 1 (M1).

The efficacy of influenza vaccines designed to induce subtype cross-reactive T cells to internal influenza antigens such as nucleoprotein (NP), which is highly conserved between all influenza A subtypes, has been demonstrated in many species of animal model [ 5– 8], and this approach has the potential to replace or supplement seasonal and pandemic-specific vaccination in humans.

Samples were tested for antibodies directed against the conserved internal nucleoprotein of influenza A viruses using a blocking enzyme-linked immunosorbent assay (bELISA) (FlockChek Avian Influenza MultiS-Screen Antibody Test Kit, IDEXX Laboratories, Westbrook, Maine, USA) following the manufacturer's instructions.

Influenza M1 is the most abundant influenza internal protein with the conserved primary structure.

T-cell epitopes in internal proteins of influenza A virus are more conserved than antibody epitopes.

In addition, heteroduplex mobility assays can be used to genetically characterize the HA and internal genes of influenza viruses (20, 37, 38 ).

Using the default outer probe radius of 10 Å in the 3V server (http://3vee.molmovdb.org/), we could not detect any internal cavity in influenza B virus HA.