Sentence examples for internal compound from inspiring English sources
These models were qualified prospectively by selecting and testing compounds from the internal compound collection.
AZ analyzed the charge category of their antibacterial project actives relative to a representative sample of their internal compound collection.
Utilizing publicly available crystal structures of NAMPT and in silico docking of our internal compound library, a NAMPT inhibitor, 1, obtained from a phenotypic screening effort was replaced with a more synthetically tractable scaffold.
Compound 7 was taken from our internal compound collection as an attractive starting point and exhibited moderate binding affinity for α1D AR and high selectivity against α1A– and α1B ARs.
However, to support the growth of the human metabolism information in the future, small molecule data were expanded by incorporating an internal compound data pool propagated from HMDB (19), LMSD (21), ChEBI (20), KEGG (17) and PubChem (22) with full InChI annotation.
The screening software was interfaced with our internal compound database, containing approximately 7100 compounds [ 9], via an in-house-built Excel application that generated automatic search lists for TargetAnalysis, and made it possible to search for the most likely adduct and/or fragment ions and to only include taxonomically relevant compounds if wanted.
A still higher impact at time of trauma may cause the fragments to cause internal compounding as well.
This low percentage is quite similar to other recent reports on Ames results at other pharmaceutical companies such as the recent report from Hillebrecht et al. from Roche [4] where 300/2335 = 13% of the internal compounds were Ames+.
Detection of contact or even internal compounds likely involve sensilla on the ovipositor [ 62] presumably after contact chemicals have been detected and evaluated.
Since the original mode satisfied all constraints set by mass balances of internal compounds along its path, the two parts must separately continue to be viable.
In the example in Figure 1a, there are three internal compounds (B, C and E), three external compounds (A, D and F), and six reactions (R1, R2, R3, R4, R5 and R6).
