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Hence, simulations are also performed on the aqueous DES solutions, which reveal the effect of water on intermolecular network of interaction existing within these DESs.
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Note that the conformation of the sugar moiety of glycosphingolipids is restricted by a network of H-bonds (Ref. 52) that involves either an OH group in the acyl chain of the ceramide (intramolecular network) or the OH group of cholesterol (intermolecular network, Fig. 3e), as further discussed below (see the section 'The outside and inside effects of cholesterol').
By forming large intermolecular networks, glycans generally exhibit highly increased solution viscosity.
On the contrary, the left-handed helical assembly through an intermolecular hydrogen-bonding network of 15-membered intermolecularly hydrogen-bonded ring between NH (Ala) and CO (the ferrocenoyl moiety of another molecule) and between NH (the cysteamine moiety of another molecule) and CO (Ala) was observed in the crystal packing of 4 composed of the L-Ala-D-Pro-NHCH2CH2SH chain.
One of the dendrimers (2) shows crystallographic S4-symmetry and intramolecular C H⋯O bonding, whereas the other (4) shows crystallographic C2-symmetry and is imbedded in a zipper-like network of intermolecular C H⋯O bonds.
Several structural features appeared to contribute to the anti-HIV potency of [5P7]CCL5, including the distinct chemokine orientation relative to the receptor, the near-complete occupancy of the receptor binding pocket, the dense network of intermolecular hydrogen bonds, and the similarity of binding determinants with the FDA-approved HIV inhibitor Maraviroc.
As shown in Figure 2 b, molecules of 1 interact via a network of intermolecular hydrogen bonds.
For example, the extensive network of intermolecular hydrogen bonds between biotin and streptavidin is known to contribute to a very high affinity interaction.
Interestingly, we observe that Pdc1 and Edc3 are able to engage in an indefinite network of intermolecular interaction that results in the formation of an oil-like droplet phase, as we observed for Dcp2 and Edc3.
An X-ray crystal structure of TPA-BDP reveals a network of CH⋯F intermolecular interactions which can contribute to rigidifying the molecular conformation.
Class B G protein-coupled receptors are activated by their cognate ligands following a two-step binding model involving a specific network of ligand-receptor intermolecular interactions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com