Sentence examples for intermolecular complexes and from inspiring English sources
These apparent changes in fluorescence behaviour indicate the differences in the nature and number of intermolecular complexes and radiationless deactivation processes in various phases.
We propose a novel approach to modulate biomolecular interactions by de novo structure-based design of noncompetitive small molecules that bind to the intermolecular complexes and make molecular contacts with both interacting partners.
Our results show that these domains are composed of intermolecular complexes and their aggregates stabilized by the neutralization effect of GB, and linked together by formation of GB triple helices.
To determine if full-length mDia1 is also a dimer, we analyzed the intact protein as well as two intermolecular complexes of N- and C-terminal fragments (Fig. 1A) using sedimentation equilibrium ultracentrifugation and MALS.
Gibbs free energies (ΔG) of individual molecules and intermolecular complexes were calculated in gromacs.
Because the major difference between KR21 and AE21 is the presence of the reactive maleimido group on the latter, and considering that noncovalent intermolecular complexes break up in the chaotropic environment of SDS PAGE, these results provide evidence that AE21 is reactive for conjugation to E275C gp120.
Intermolecular complexes between tropomyosin's ends have Kds of 0.5 20 µM and are in equilibrium between folded and unfolded conformations [5], [6], [49].
Especially the propensity of selected sequence motifs for intramolecular folding of the probes and/or the targets and also for the formation of special intermolecular complexes are expected to involve longer runs of subsequent nucleotides causing deviations from the additivity assumption (Eq. (16)).
We report that PCPP can spontaneously self-assemble into intermolecular complexes with common formulation excipients − polyethers in aqueous solutions at neutral pH through the establishment of hydrogen bonds.
Intermolecular interaction energies for representative configurations of intermolecular complexes were analyzed using the supermolecular approach at the MP2/6-311+G∗ level, which resulted in substantial interaction strengths for all the three forms of intermolecular interactions.
Titration in the presence of other ligands, rapidly provides information on the mechanism of action of the test compound, identifying the intermolecular complexes that are relevant for structure-based design.
