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In the intermittent stimulation protocol (iTBS), pulses were delivered in intervals of 2s-stimulation-trains followed by a 8s-pause for a total of 190 s.
This may be related to the lack of transcriptional response of ACAN to long-term intermittent stimulation suggesting that the mechanosensitivity of this particular gene decreased over the culture duration, while other chondrogenic markers did not (Fig. 6d).
To this end, we used the procedure of intermittent stimulation to induce rivalry [11].
How might the intermittent stimulation of a single whisker account for plasticity within such a large volume of cortex?
Muscles were subjected to an intermittent stimulation protocol in which a 333 ms stimulus train per minute was administered over a range of 1 to 120 Hz.
In conclusion, this study indicates that a relatively modest intervention, intermittent stimulation of a single whisker, if timed appropriately, can have the dramatic effect of preventing the cortical consequences of ischemia.
Similar(39)
This list contains the following: intermittent photic stimulation (IPS), hyperventilation, sleep deprivation, sleep (induced/natural/after sleep deprivation), awakening, medication administered during the recording, manual eye closure/opening, auditory stimulation, nociceptive stimulation, physical effort, cognitive tasks, and "other modulators and procedures" (specified in free text).
We further demonstrate that intermittent biaxial stimulation facilitated by our system significantly enhances the accumulation of cartilage-specific ECM.
Besides, it also detects paroxysmal abnormalities and evaluates the effects of intermittent photic stimulation and hyperventilation on the EEG.
To investigate whether chondrocytes remain mechanosensitive after prolonged intermittent mechanical stimulation, we analysed chondrocyte gene expression in free swelling and loaded cartilage constructs 2 h after the last loading cycle had ceased (Fig. 6d).
We further demonstrate that intermittent biaxial stimulation of tissue-engineered constructs based on clinically relevant cells and biomaterials enhances the biosynthesis and accumulation of hyaline cartilage-specific ECM, yielding neotissues with superior native-like biochemical properties.
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