Sentence examples for intermediates that trigger from inspiring English sources
The loss of TREX1 activity may result in the accumulation of double-stranded DNA (dsDNA) degradation intermediates that trigger autoimmune activation.
The authors use genome wide proteomics and lipidomics to show that loss of GARP leads to the accumulation of long chain base sphingolipid synthesis intermediates that may trigger toxicity by release of zinc from the vacuole.
During infection the replication of RNA viruses generate long dsRNA intermediate molecules that triggers the synthesis of small interfering RNAs (siRNAs) [ 4].
The manifestation of the AD clinical syndrome is the final culmination of a sequence of events beginning with genetic and environmental risk factors that trigger intermediate pathological changes, synapse loss and cell death, and ultimately cognitive decline and dementia.
In addition, we show that this regulation of the ceramide synthase complex is important for preventing accumulation of pathway intermediates that would otherwise compromise cell growth by triggering an inappropriate autophagic response.
The critical trigger is likely represented by problematic intermediates that cannot be completely or efficiently repaired by NER.
Once activated, HER receptors initiate the recruitment of intermediate signaling proteins, which subsequently activate downstream signal cascades that trigger the cellular responses [ 2].
The replication-defective nature of HERVs may allow for the accumulation of replication intermediates that would not normally be found in abundance, and triggering of yet-undiscovered innate sensors.
Some antidepressants produce yawns that trigger orgasms.
It will also be interesting to determine whether the actual DNA that triggers cGAS corresponds to fully reverse-transcribed cDNA, intermediates of reverse transcription or to aberrant, non-productive RT products.
