For example, in the subsection headed "Direct biochemical detection of backsplicing intermediates supports the existence of a lariat intermediate", the statement "remarkably high levels" appears to be solely based on a robust band observed after 35 cycles of PCR.
In our cohort of patients with severe PAP and hematologic diseases, serum GM-CSF level were low to intermediate, supporting some up regulation of GM-CSF.
We anticipate that only variants and quality scores will be loaded into the system, whereas all raw and intermediate supporting data will be retained by the reporting laboratory systems, to the extent they are retained at all.
The identification of a key intermediate supported a proposed NRPS-mediated mechanism of sulfazecin biosynthesis and β-lactam ring formation distinct from the nocardicins, another NRPS-derived subclass of monocyclic β-lactam.
This suggests that the helicase double mutants accumulate toxic HR intermediates, further supporting the need for tight regulation of recombination during DNA replication [22,39].
For almost all response variables, B. improvisus performed slightly better at low and intermediate salinities, supporting the idea that B. improvisus is one of few truly brackish species.
Likewise, nimodipine (the subject of recent trials in AD patients) provided intermediate protection, supporting ∼60% survival at 10 μM, but also had considerable deleterious effects at higher concentrations.
The presence of these intermediates was supported by DSC experiments.
We recovered two classes of partially-rearranged molecules, including potential unscrambling intermediates that support both possible pathways (Figure 4).
Pier, in building construction, vertical loadbearing member such as an intermediate support for adjacent ends of two bridge spans.
