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Finally, the process of DNA repair by homologous recombination (HR) generates intermediates linking chromatids.
Specifically, we identified the proinflammatory sequelae of C5a C5aR interactions and the recruitment of neutrophils as the critical intermediates linking pathogenic aPL antibodies to fetal damage.
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This glucose step-function induced a dynamic response from the metabolic intermediates linked to this central nutrient.
Here, we observed that multiple chromophore environments within the native state are averaged in the trapped intermediate, linking chromophore flexibility to mispacking in the trapped intermediate.
DAG has long been discussed as a key lipid intermediate linking nutrient excess to dysregulation of insulin action [39].
As noted by Hendriksen [ 2], often there is only a single unknown intermediate linking two consecutive elementary reactions.
Glyoxylate formation occurs following the hydrolysis of dehydroglycine, the latter of which is the common intermediate linking thiamine biosynthesis in aerobes and anaerobes.
This suggests that if a hyperinflammatory phenotype is a mechanistic intermediate linking accelerated periodontal destruction and diabetes, it is likely to be a localized inflammatory response restricted to the gingival tissues.
Distinguishing between these possibilities is not easy because a defect in either process can lead to similar phenotypes relating to chromosome segregation failure resulting from unreplicated DNA or persistent recombination intermediates physically linking the sister chromatids (Fig. 1).
… found, not one, but three intermediate species linking land mammals to the archeocetes, the oldest swimming mammals.
The intermediate phase linking the lamellae and the amorphous layers is assumed to form a surface layer around each lamella and its role in the yield behavior of HDPE is discussed.
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