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It is well known that the stabilizing osmolytes are preferentially excluded from the intermediate vicinity of the protein surface through a solvophobic interaction between peptide backbone and side chain on the protein surface and the protecting osmolytes [ 39].
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It has been demonstrated in a rabbit model, that an adaptive immune response in defects from the patellar and trochlear groove upon implantation of an allogenic matrix is primarily intermediated by the vicinity of the synovium and not in contact with the blood supply (Arzi et al. 2015).
In this case, high energetic chemical reactions instead of leading directly to luminescent species, transfer the energy of the intermediate excited complex to vicinity fluorophores.
Through this analysis, the minimization of Hϕ of the intermediate compounds in the vicinity of the anisotropy transition, which indicates the existence of an isotropic easy magnetization surface, is highlighted as a basic design requirement for the fabrication of soft hexagonal ferrites with increased μ′ and μ″ values.
In addition, storage of deep groundwater at intermediate depths in the vicinity of the ASW results in a ternary mixture of water entering the well at intermediate depths.
The center-mounted baffle was effective under intermediate fill levels in the vicinity of 50%, while the bottom mounted baffle was effective only under very low fill heights.
These results suggest that, in vivo, the axon pathway is impaired when axons from TTL−/− embryos navigate in the vicinity of their intermediate target, the floor plate, that is a source of both diffusible and contact cues [11] during ION axon outgrowth and neuronal migration.
Principally, the guanidinium group could participate in all five reactions depicted above and could support substrate binding as well as potentially keep the postulated reaction intermediate, hypochlorite (or O Cl), in the vicinity of the ferryl oxygen for the recombination step and O2 formation.
Lys167 forms the Schiff base intermediate, whereas Lys201, which is in close vicinity to the reactive lysine residue, is responsible for the perturbed pKa of Lys167 and, hence, also a key residue in the reaction mechanism.
Wells with high [U] or [Rn] are located within the granitic plutons or their vicinity at local (SI Table S1) and intermediate spatial scales in greater Augusta and the regional spatial scale in Maine.
Because of the lack of resolution, we do not know if in the presence of the ARF1-locked mutant, transport intermediates were actually produced but remained in the vicinity of the donor Golgi in a coated form, or if the ARF1 mutant prevented complete formation of COPI vesicles.
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