It was not until Wilco Kelderman of the team – starting 143rd as opposed to Durbridge starting 19th – had set quicker times at each of the intermediate timing points that Durbridge's time came under threat from another rider, and Kelderman ultimately beat Durbridge's time by twelve seconds, despite almost overshooting the final corner, narrowly avoiding the barriers on the outside of the corner.
De Gendt, who won the opening stage of the race in 2011, ultimately picked up the polka-dot jersey for the lead in the mountains classification, as he held the quickest time to the intermediate timing point, at the summit of the Côte des Dix-sept Tournants.
2.06pm BST It is still dry at the finish line but at the second intermediate timing there is rain and plenty of it.
To decide what a final pattern is, and when exactly it occurs, is always arbitrary to some degree, while transient features (such as intermediate stages and the timing of their transitions) are clearly important when considering the function and dynamics of developmental processes.
To allow for detection of incomplete or defective replication intermediates, or of altered timing of chromosomal origin function, we investigated the effect of deleting HAT1 on the activity of specific chromosomal origins (ARS305 and ARS1) using neutral two-dimensional gel electrophoresis.
"Because brain size in Homo erectus is intermediate between that of chimps and modern humans, we have assumed that the timing of dental development was intermediate also," says Zihlman, whose study appears in the 20 July Proceedings of the National Academy of Sciences.
Because intermediate scans to determine the exact timing of progression were not performed, and arterial disease improved or stabilized at subsequent angiography, we had no proof of progression beyond 6 months, and therefore classified the course of arteriopathy as TCA in these three patients.
MVA has a complex genome and its promoters are classified based on the timing of gene expression into early, intermediate and late.
Temperature increases can also impact development rate and timing of release of microparasites from intermediate hosts, potentially increasing densities and and extending exposure periods for migratory fish (Stocking et al. 2006; Ray et al. 2012; Chiaramonte 2013).
To further refine the timing of the TLO recombination events, we assayed isolates at intermediate time points during passaging for either the ancestral or evolved TLO organization.
